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ORIGINAL ARTICLE
Year : 2020  |  Volume : 9  |  Issue : 2  |  Page : 51-55

Effect of Jintiange capsule on acute bone atrophy resulting from wrist fractures: A randomized controlled trial


1 Department of Orthopedics, the Second Hospital of Tangshan (Orthopaedic Hospital Affiliated to North China University of Science and Technology), Tangshan 063000, China
2 Tangjiazhuang Hospital of Kailuan (Group) Limited Liability Corporation, Tangshan, 063100, China
3 Tangshan gongren hospital, Tangshan, 063000, China

Correspondence Address:
Hong-Wei Zhang
Department of Orthopedics, the Second Hospital of Tangshan (Orthopaedic Hospital Affiliated to North China University of Science and Technology), Tangshan 063000
China
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Source of Support: This study was supported by the Science and Technology Support Project of Hebei Traditional Chinese Medicine Administration (No. 2019210), Conflict of Interest: None


DOI: 10.4103/2221-6189.281312

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Objective: To investigate the efficacy of Jintiange capsule in the treatment of acute bone atrophy due to wrist fractures. Methods: Participants were randomly allocated into two groups, i.e. the treatment group and the control groups. All patients received functional rehabilitation exercise. Patients in the treatment group received Jintiange capsule orally, while the control group received placebos. At 3 and 6 months after the treatment, Cooney score, hand grip and pinch strength were measured. The visual analogue scale (VAS) was applied, and safety events were recorded. Results: No loss occurred during 6 months of follow-up after treatment. Before the treatment, there was no statistically significant difference between the two groups in Cooney score, hand grip strength, hand pinch strength or VAS score (all P>0.05). At 3 and 6 months after the treatment, the Cooney core, hand grip and pinch strength increased, and the VAS were decreased in all patients. The treatment group showed significantly greater improvement than the control group (P<0.05). In additional, both groups showed few side effects. Conclusions: Jintiange capsule can improve the function of the wrist joint and alleviate the pain of fracture. It is safe and effective for treating acute bone atrophy.


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