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CASE REPORT
Year : 2020  |  Volume : 9  |  Issue : 2  |  Page : 89-92

Ruptured splenic abscess and splenic vein thrombosis secondary to melioidosis: A case report


Medical Department, Sarawak General Hospital, Ministry of Health, 93586 Kuching, Malaysia

Correspondence Address:
Chang Chee Yik
Medical Department, Sarawak General Hospital, Ministry of Health, 93586 Kuching
Malaysia
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2221-6189.281326

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Rationale: Burkholderia pseudomallei is a Gram-negative bacterium and the causative pathogen of melioidosis, which manifests with a broad spectrum of clinical syndromes. Melioidosis is associated with high mortality and is endemic across tropical areas, especially in Southeast Asia and northern Australia. Patient concern: A 24-year-old diabetic male complained of fever and left upper quadrant abdominal pain for one-week duration. Diagnosis: Melioidosis with ruptured splenic abscess and splenic vein thrombosis. Interventions: Antimicrobial therapy (intensive therapy: intravenous ceftazidime, eradication therapy: oral trimethoprim- sulfamethoxazole), and anti-coagulation (enoxaparin, then warfarin). Outcomes: Resolution of splenic abscess and splenic vein thrombosis. Lessons: Both splenic abscess and splenic vein thrombosis are uncommon but severe complications associated with melioidosis. Ultrasound is useful for diagnosis and monitoring response to treatment in such cases.


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