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Year : 2021  |  Volume : 10  |  Issue : 6  |  Page : 258-260

Dengue fever leading to acute dengue hemorrhagic leukoencephalitis: A case report

1 Department of Anaesthesiology & Critical Care, Armed Forces Medical College, Pune 411040, India
2 Department of Neurology, Command Hospital, Pune 411040, India

Correspondence Address:
Ankur Gupta
Department of Anaesthesiology & Critical Care, Armed Forces Medical College, Pune 411040
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2221-6189.330746

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Rationale: Dengue fever is a prevalent tropical infectious disease that has a broad panorama of presentations from mild febrile illness to life-threatening manifestations in the form of dengue hemorrhagic fever and dengue shock syndrome. Patient’s concerns: A 20-year-old male presented with a 2-day history of fever, multiple episodes of vomiting, and altered sensorium. Diagnosis: Dengue fever leading to acute hemorrhagic leukoencephalitis. Interventions: Multiple transfusions of single donor platelets, intravenous methylprednisolone, intravenous immunoglobulin, anti-seizure prophylaxis, and broad-spectrum antibiotics. Outcomes: Repeat brain magnetic resonance imaging showed resolution of lesions. The patient was subsequently discharged from the hospital in a healthy state. Lessons: This report helps us to gain a better understanding of the patient’s presentation, which will help to improve the timely recognition and prevention of this rare devastating presentation.

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